Paget's bone disease, clinical case report

Paget's disease is a disorder affecting bone metabolism due to accelerated bone remodeling. It mainly affects the pelvis, spine, lower extremity bones, and skull. It is believed to be the result of a combination of genetic and environmental factors; its incidence has decreased in recent years. Symptoms are usually absent; however, some report bone pain. Treatment aimed to prevent bone remodeling by using bisphosphonates. We present the case of a 34-year-old female with pain and bone deformity of the knee of 5 months of evolution, in radiographs and scintigraphy, with signs compatible with Paget's disease. Bisphosphonates were administered, and there was improvement after 3 months. This is a relevant case because the incidence of Paget's disease is higher in men over 40 years of age.