MRI-derived radiomics model for predicting intratumoral tertiary lymphoid structures in soft tissue sarcoma
Intratumoral tertiary lymphoid structure status in patients with soft tissue sarcomas was accurately predicted by an MRI-derived radiomics model. The combined radiomics model showed superior performance compared to both the intratumoral and peritumoral radiomics models. Progression-free survival was significantly longer in patients with a high Rad-score (≥ 0.5) in the development, internal validation, and external validation cohorts.
Authors
- Xianglong Shi
- Dapeng Hao (ORCID: https://orcid.org/0000-0002-4215-7116)
- He‐xiang Wang (ORCID: https://orcid.org/0000-0001-8313-7632)
- Ruizhi Zhou (ORCID: https://orcid.org/0000-0003-3913-8640)
- Yuanyuan Zong
- Liping Wang (ORCID: https://orcid.org/0000-0001-6893-3809)
- Tongyu Wang (ORCID: https://orcid.org/0009-0008-6618-3088)
- Feng Hou (ORCID: https://orcid.org/0000-0002-1205-0131)
- Hao Zhong (ORCID: https://orcid.org/0009-0000-7939-5911)
- Song Gao (ORCID: https://orcid.org/0000-0003-4359-6302)
- Jiangfei Yang
Institutions
- Qingdao University (CN)
- Yuhuangding Hospital (CN)
- Shandong Provincial Hospital (CN)
- Affiliated Hospital of Qingdao University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Insights into Imaging
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1186/s13244-025-02086-3
- Citations
- 1
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- National Natural Science Foundation of China