A Novel TRG-N Prognostic Classification System for Esophageal Cancer Undergoing Neoadjuvant Therapy Followed by Esophagectomy
The TRG-N classification demonstrated comparable prognostic performance to the AJCC ypTNM classification for esophageal adenocarcinoma but showed superior prognostic value for esophageal squamous cell carcinoma, making it a potentially more effective tool for risk stratification in esophageal cancer patients.
Authors
- Rob H.A. Verhoeven (ORCID: https://orcid.org/0000-0001-9678-1611)
- Peter S.N. van Rossum (ORCID: https://orcid.org/0000-0003-4243-8388)
- Lucas Goense (ORCID: https://orcid.org/0000-0001-5824-8736)
- Richard van Hillegersberg (ORCID: https://orcid.org/0000-0002-7134-261X)
- Marije Slingerland (ORCID: https://orcid.org/0000-0002-4181-8656)
- Stella Mook (ORCID: https://orcid.org/0000-0002-0313-814X)
- Jan Erik Freund (ORCID: https://orcid.org/0000-0001-9296-1148)
- Jelle P. H. Ruurda (ORCID: https://orcid.org/0000-0001-6584-1677)
- Nadia Haj Mohammad (ORCID: https://orcid.org/0000-0002-4688-2921)
- Zhouqiao Wu (ORCID: https://orcid.org/0000-0001-9222-181X)
- Jingpu Wang
Institutions
- Utrecht University (NL)
- Peking University (CN)
- Leiden University Medical Center (NL)
- University Medical Center Utrecht (NL)
- Peking University Cancer Hospital (CN)
- Netherlands Comprehensive Cancer Organisation (NL)
- Amsterdam University Medical Centers (NL)
- Cancer Center Amsterdam (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Annals of Surgery
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1097/sla.0000000000006869
- Citations
- 1
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Amgen
- Bristol-Myers Squibb
- China Scholarship Council
- Daiichi Sankyo Europe