Rapid thawing of fresh frozen plasma with a 45°C dry tempering system maintains critical coagulation activities
Dry tempering is useful for thawing FFP in real-world clinical situations. In contrast to open water baths, dry tempering systems could be incorporated into ambulance and emergency response vehicles responding to traumatic bleeding events. Uniquely, the new dry tempering system at 45°C could save precious minutes in a massive transfusion protocol while preserving FFP coagulation activity.
Authors
- Kosaku Mimura (ORCID: https://orcid.org/0000-0003-2565-154X)
- Hitoshi Ohto
- Shunya Rikimaru
- Hiroki Shimura (ORCID: https://orcid.org/0000-0002-9770-2943)
- Nozomi Takano
- Kazuhiko Ikeda (ORCID: https://orcid.org/0000-0002-5269-269X)
- Keiji Minakawa
- Kenneth E. Nollet
- Koki Ueda
- Kinuyo Kawabata (ORCID: https://orcid.org/0009-0000-5889-6274)
- Mitsuhiko Tadano
Institutions
- Fukushima Medical University (JP)
- Fukushima Medical University Hospital (JP)
Publication Details
- Journal
- Transfusion
- Published
- 2025-09-22
- DOI
- https://doi.org/10.1111/trf.18426
- Primary Topic
- Freezing and Crystallization Processes
- Type
- article
- Field-Weighted Citation Impact
- 0.00