Design and synthesis of novel <i>N</i> -phenyl-4-pyrimidine-diamine BCL6 inhibitors with <i>anti</i> -tumor activities
These findings highlight the potential of pyrimidinediamine-based scaffolds as novel BCL6 inhibitors, warranting further structural optimization to improve their efficacy.
Authors
- Yihua Chen (ORCID: https://orcid.org/0000-0003-1733-7980)
- Yajing Xing (ORCID: https://orcid.org/0000-0003-2649-3627)
- Yangrui Peng (ORCID: https://orcid.org/0000-0003-4031-447X)
- Zhengfang Yi (ORCID: https://orcid.org/0000-0003-3592-9912)
- Yan Li (ORCID: https://orcid.org/0000-0002-2781-2119)
- Dongxia Huang (ORCID: https://orcid.org/0000-0003-3346-3717)
- Jiuqing Xie
Institutions
- Chongqing University (CN)
- Yunnan University (CN)
- Kunming Medical University (CN)
- Shanghai Changning Maternity and Infant Health Hospital (CN)
- East China Normal University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Future Medicinal Chemistry
- Published
- 2025-09-21
- DOI
- https://doi.org/10.1080/17568919.2025.2561541
- Citations
- 2
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 2.09