Human epidermal growth factor receptor 2 and proliferation Ki-67 biomarkers using a tissue microarray to refine the histopathological subtyping of hydatidiform moles: Limitations and prognostic value
Ki-67 and HER2 markers may be useful for the diagnosis and prediction of HM development, providing alternative targeted therapies. This study needs to be interpreted with caution due to its small sample size, high sample exclusion rate, and the absence of significant associations between biomarkers and clinical outcomes.
Authors
- Karin Soares Cunha (ORCID: https://orcid.org/0000-0002-5647-282X)
- Antônio Braga (ORCID: https://orcid.org/0000-0002-2942-6182)
- Consuelo Lozoya López
- Ana Carolina Gonçalves Brito
- Neuzenir da Silva de Abreu Oliveira (ORCID: https://orcid.org/0000-0003-3733-0022)
- Ana Luísa Figueira Gouvêa (ORCID: https://orcid.org/0000-0003-1179-200X)
- Fabiana Resende Rodrigues (ORCID: https://orcid.org/0000-0001-5062-1065)
Institutions
- Universidade Federal Fluminense (BR)
- University of Vassouras (BR)
- Hospital Universitário Antônio Pedro (BR)
Publication Details
- Journal
- Clinics
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.clinsp.2025.100766
- Primary Topic
- Gestational Trophoblastic Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00