[Overemphasized surgical issues:the history, misconceptions, controversies, and future directions of lymph node detection thresholds and dissection range in colon cancer].

The number of lymph nodes detected in colon cancer is influenced by various factors. The arbitrary application of the 12-lymph node detection threshold as a quality control standard is unreasonable. Overemphasis on the number of lymph nodes may result in an unnecessarily extensive dissection, while existing evidence shows no survival benefit from routine D3 lymphadenectomy. This article systematically reviews the origin, rationale, influencing factors, and common misconceptions surrounding the lymph node detection threshold. It also looks ahead to the trend of narrowing the scope of lymphadenectomy in colon cancer and the potential for personalized dissection strategies.

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Publication Details

Journal
PubMed
Published
2025-09-25
DOI
https://doi.org/10.3760/cma.j.cn441530-20241205-00397
Primary Topic
Colorectal Cancer Surgical Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

[Overemphasized surgical issues:the history, misconceptions, controversies, and future directions of lymph node detection thresholds and dissection range in colon cancer].

Aiwen Wu, L Wang, Y Y Gao, Yi Xiao et al.
PubMed
Colorectal Cancer Surgical Treatments
article

[Overemphasized surgical issues:the history, misconceptions, controversies, and future directions of lymph node detection thresholds and dissection range in colon cancer].

Aiwen Wu, L Wang, Y Y Gao, Yi Xiao, Junyang Lu
article en

Abstract

The number of lymph nodes detected in colon cancer is influenced by various factors. The arbitrary application of the 12-lymph node detection threshold as a quality control standard is unreasonable. Overemphasis on the number of lymph nodes may result in an unnecessarily extensive dissection, while existing evidence shows no survival benefit from routine D3 lymphadenectomy. This article systematically reviews the origin, rationale, influencing factors, and common misconceptions surrounding the lymph node detection threshold. It also looks ahead to the trend of narrowing the scope of lymphadenectomy in colon cancer and the potential for personalized dissection strategies.

PubMedVol. 28(9)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN)
Openalex Percentile: Top 65%
Colorectal Cancer Surgical Treatments
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