Determinants of airway morphology in asthma: Inflammatory and noninflammatory factors
BMI, asthma duration, sinusitis, and the presence of bronchiectasis are significant determinants of airway tree morphology in asthma, alongside inflammation and mucus plugs. Both inflammatory and noninflammatory biomarkers were associated with low TAC.
Authors
- Satoshi Konno (ORCID: https://orcid.org/0000-0001-6439-2443)
- Ichizo Tsujino (ORCID: https://orcid.org/0000-0002-0196-9572)
- Naoya Tanabe (ORCID: https://orcid.org/0000-0002-7481-0212)
- Kazufumi Okada (ORCID: https://orcid.org/0000-0002-6537-376X)
- Akira Oguma (ORCID: https://orcid.org/0000-0003-3732-8483)
- Kaoruko Shimizu (ORCID: https://orcid.org/0000-0002-2785-4634)
- Houman Goudarzi (ORCID: https://orcid.org/0000-0003-1145-8917)
- Hirokazu Kimura (ORCID: https://orcid.org/0000-0002-2725-177X)
- Jun Miyata (ORCID: https://orcid.org/0000-0002-3189-1702)
- Masaharu Nishimura (ORCID: https://orcid.org/0000-0002-6456-4361)
- Yuji Nakamaru (ORCID: https://orcid.org/0000-0002-9045-4617)
- Nobuyasu Wakazono (ORCID: https://orcid.org/0000-0003-3865-8660)
- Shotaro Chubachi (ORCID: https://orcid.org/0000-0002-5046-3762)
- Hironi Makira
Institutions
- Sapporo University (JP)
- Keio University (JP)
- Hokkaido University (JP)
- Kyoto University (JP)
- Oji General Hospital (JP)
- Hokkaido University Hospital (JP)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology Global
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1016/j.jacig.2025.100555
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00