Multi-omics Approaches to CCAAT/Enhancer-Binding Protein Beta in Oral Squamous Cell Carcinoma: Crosstalk Between Tumor Cells and Tumor-Associated Macrophages Driving Disease Progression
CEBPB activated GAS6 transcription in metastatic OSCC cells. The CE-BPB/GAS6 axis in metastatic OSCC cells enhanced their chemotaxis toward macrophages and promoted the M2 polarization of macrophages, thereby facilitating the establishment of an immunosuppressive microenvironment.
Authors
- Lin‐Yu Jin (ORCID: https://orcid.org/0000-0001-6305-0521)
- Yongle Qiu (ORCID: https://orcid.org/0000-0002-5118-815X)
- Jilun Liu
- Xin Liu (ORCID: https://orcid.org/0000-0002-0083-1061)
- Min Li (ORCID: https://orcid.org/0000-0002-5765-4158)
- Wenjing Wang (ORCID: https://orcid.org/0000-0001-8522-078X)
- Wenjuan Zhang (ORCID: https://orcid.org/0000-0001-5434-5192)
- Ruonan Sun
Institutions
- Hebei Medical University (CN)
- Handan College (CN)
- Second Hospital of Hebei Medical University (CN)
- Fourth Hospital of Hebei Medical University (CN)
- First Hospital of Shijiazhuang (CN)
Publication Details
- Journal
- Current Cancer Drug Targets
- Published
- 2025-09-18
- DOI
- https://doi.org/10.2174/0115680096387374250823190214
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00