Left bundle branch area pacing vs right ventricular pacing for atrioventricular block: the MELOS RELOADED study
This is the first large study demonstrating the long-term survival benefit of LBBAP. This strengthens the use of LBBAP in AVB patients with preserved/mildly reduced LVEF while awaiting the results of randomized trials. Confirmation of left bundle branch capture seems advisable to achieve optimal results with LBBAP.
Authors
- Óscar Cano (ORCID: https://orcid.org/0000-0001-6783-0138)
- Philipp Krisai (ORCID: https://orcid.org/0000-0002-4367-2363)
- Wim Huybrechts (ORCID: https://orcid.org/0000-0002-2964-8068)
- David Žižek (ORCID: https://orcid.org/0000-0001-5029-3989)
- Leonard M. Rademakers (ORCID: https://orcid.org/0000-0001-6106-7354)
- Emine Özpak (ORCID: https://orcid.org/0000-0002-5813-2335)
- Karol Čurila (ORCID: https://orcid.org/0000-0003-3523-6358)
- Francesco Deluca
- Paweł Moskal (ORCID: https://orcid.org/0000-0002-4229-3548)
- Jan De Pooter (ORCID: https://orcid.org/0000-0002-3135-8676)
- Kevin Vernooy (ORCID: https://orcid.org/0000-0002-8818-5964)
- Domenico Grieco (ORCID: https://orcid.org/0000-0002-3899-3023)
- Haran Burri (ORCID: https://orcid.org/0000-0002-4393-5338)
- Valérian Valiton (ORCID: https://orcid.org/0000-0003-4118-2915)
- Zachary I. Whinnett (ORCID: https://orcid.org/0000-0002-2775-5126)
- Francesco Zanon (ORCID: https://orcid.org/0000-0003-2673-3918)
- Cătălin Pestrea (ORCID: https://orcid.org/0000-0002-0840-1736)
- Petr Štros
- Javier Navarrete‐Navarro (ORCID: https://orcid.org/0000-0002-9131-2872)
- Justin Luermans (ORCID: https://orcid.org/0000-0001-9598-2286)
- Ecaterina Cicală (ORCID: https://orcid.org/0000-0002-1641-2531)
- Marek Jastrzębski (ORCID: https://orcid.org/0000-0002-3318-6601)
- Grzegorz Kiełbasa (ORCID: https://orcid.org/0000-0001-5785-8751)
Institutions
- Jagiellonian University (PL)
- Radboud University Nijmegen (NL)
- University of Antwerp (BE)
- University of Basel (CH)
- Charles University (CZ)
- Clinical Emergency Hospital Bucharest (RO)
- Maastricht University Medical Centre (NL)
- Ghent University Hospital (BE)
- Catharina Ziekenhuis (NL)
- Ljubljana University Medical Centre (SI)
- University Hospital of Basel (CH)
- Hospital Universitari i Politècnic La Fe (ES)
- Transylvania University of Brașov (RO)
- Hospital Base (CL)
- Centro de Investigación en Red en Enfermedades Cardiovasculares (ES)
- Lung Institute (US)
- Antwerp University Hospital (BE)
- University Hospital of Geneva (CH)
- Policlinico Casilino (IT)
- Ospedale Santa Maria della Misericordia di Rovigo (IT)
- University Hospital Kralovske Vinohrady (CZ)
- Fundaţia pentru Formare Profesională şi Învăţământ Preuniversitar - Viitor (RO)
- Instituto de Investigación Sanitaria La Fe (ES)
- Imperial College London (GB)
Publication Details
- Journal
- European Heart Journal
- Published
- 2025-08-29
- DOI
- https://doi.org/10.1093/eurheartj/ehaf699
- Citations
- 10
- Primary Topic
- Cardiac pacing and defibrillation studies
- Type
- article
- Field-Weighted Citation Impact
- 13.88