Exploring the Therapeutic Mechanism of Chai-hu Long-gu Mu-li Decoction for Treating Insomnia and Anxiety Disorders based on NetworkPharmacology and Experimental Validation

This study provides new insight into the molecular mechanisms underlying the homotherapy- for-heteropathy efficacy of CLMD in treating both insomnia and anxiety.

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Publication Details

Journal
Combinatorial Chemistry & High Throughput Screening
Published
2025-09-18
DOI
https://doi.org/10.2174/0113862073388549250828182807
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Exploring the Therapeutic Mechanism of Chai-hu Long-gu Mu-li Decoction for Treating Insomnia and Anxiety Disorders based on NetworkPharmacology and Experimental Validation

Chen Sun, Fuping Xu, Guang‐Ping Ruan, Yuxuan Luo et al.
Combinatorial Chemistry & High Throughput Screening
Tryptophan and brain disorders
article

Exploring the Therapeutic Mechanism of Chai-hu Long-gu Mu-li Decoction for Treating Insomnia and Anxiety Disorders based on NetworkPharmacology and Experimental Validation

Chen Sun, Fuping Xu, Guang‐Ping Ruan, Yuxuan Luo, Lei Cai, Shaoyi Fan, Yiwei Chen, Xuejun Hu
article en

Abstract

This study provides new insight into the molecular mechanisms underlying the homotherapy- for-heteropathy efficacy of CLMD in treating both insomnia and anxiety.

Combinatorial Chemistry & High Throughput ScreeningVol. 28
Guangzhou University of Chinese Medicine (CN), Sun Yat-sen University (CN), Guangdong Laboratory Animals Monitoring Institute (CN), Third Affiliated Hospital of Sun Yat-sen University (CN)
Openalex Percentile: Top 74%
Tryptophan and brain disorders
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Exploring the Therapeutic Mechanism of Chai-hu Long-gu Mu-li Decoction for Treating Insomnia and Anxiety Disorders based on NetworkPharmacology and Experimental Validation — Chen Sun, Fuping Xu, et al. · Combinatorial Chemistry & High Throughput Screening (2025) | TGRS Research Map | TGRS