Association between genetic mutations in lung adenocarcinoma and adult body mass index: a retrospective cohort study
This study reveals a significant association between BMI and ADC gene mutations, demonstrating that elevated BMI levels correlate negatively with mutation risk within the specific range of 21.08 to 22.86 kg/m². Furthermore, the rate of gene mutation may be relatively high in women under the age of 60 who do not smoke or drink. This study may assist clinicians in preliminarily assessing the gene mutation status of patients with ADC.
Authors
- Yan Wu (ORCID: https://orcid.org/0000-0002-0928-6127)
- Depeng Jiang (ORCID: https://orcid.org/0000-0003-2694-7449)
- Lei Yang (ORCID: https://orcid.org/0000-0002-6351-0521)
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-09-22
- DOI
- https://doi.org/10.3389/fonc.2025.1661143
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chongqing Medical University