Lack of Association Between COL1A1 rs1800012 Polymorphism and Anterior Open Bite Malocclusion in a Turkish Case–Control Cohort
This study provides no evidence of association between <i>COL1A1</i> rs1800012 and anterior open bite in this Turkish cohort. The relatively small sample size, the rarity of the TT genotype, and the multifactorial nature of craniofacial development represent important limitations. Larger, multi-gene, and functionally integrated studies are required to clarify the genetic architecture of open bite malocclusion.
Authors
- Elvan Önem Özbilen (ORCID: https://orcid.org/0000-0002-5052-2320)
- Tolga Polat (ORCID: https://orcid.org/0000-0002-2064-6613)
- Özlem Özge Yılmaz (ORCID: https://orcid.org/0000-0002-4085-6159)
- Beste Tacal Aslan (ORCID: https://orcid.org/0000-0001-5271-7917)
Institutions
- Marmara University (TR)
Publication Details
- Journal
- Genes
- Published
- 2025-09-23
- DOI
- https://doi.org/10.3390/genes16101122
- Primary Topic
- Cell Adhesion Molecules Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00