Mobilisation-with-movement induces analgesia during exercise but exercise alone is not analgesic in people with lateral elbow tendinopathy: An assessor blinded, randomised crossover trial

When combined with pain-provoking exercise, MWM produced hypoalgesic effects. Effects were largest when measured locally but also present at remote site, suggesting that both reduced stimulation of peripheral nociceptors and activation of descending pain inhibitory pathways may underpin its efficacy. By mitigating exercise-related pain and improving grip force, MWM may facilitate better adherence to exercise-based rehabilitation programs.