Integrated analysis and experimental validation of E2F2 as a potential prognostic biomarker and its oncogenic roles in serous ovarian cancer
High E2F2 expression marks poor prognosis and immune cell infiltration in SOCs and thus acts as an independent risk factor. It may serve as a potential biomarker for diagnosis, patient stratification, and guiding personalized therapy. Further research could enhance SOC management.
Authors
- Liwen Zhang (ORCID: https://orcid.org/0000-0002-6452-6568)
- Fengyin Jiang
- Lina Yang (ORCID: https://orcid.org/0009-0001-9204-3264)
- Fei He (ORCID: https://orcid.org/0000-0002-4828-7624)
- Rujun Chen (ORCID: https://orcid.org/0000-0002-9451-6280)
Institutions
- Fudan University (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-09-23
- DOI
- https://doi.org/10.3389/fmolb.2025.1661558
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00