Potential histopathological pitfalls in biopsies for endometriosis, related to the use of cellulose based material in prior surgical procedures

Cellulose-based materials used in endometriosis surgeries, can trigger histiocytic reactions that mimic mucinous lesions. These two cases highlight diagnostic challenges due to misleading special stain positivity. Accurate biopsy interpretation requires attention to histologic features and detailed surgical history to avoid misdiagnosis.