Intranasal methylene blue administration confers neuroprotection in rats subjected to exhaustive exercise training
Our findings demonstrate the neuroprotective effects of intranasal MB against exhaustive exercise-induced neurological deficits. This suggests that MB is a promising therapeutic agent for preventing the adverse neurological consequences of extreme physical exertion.
Authors
- Xu Ma (ORCID: https://orcid.org/0000-0002-1001-8760)
- Guangcong Peng (ORCID: https://orcid.org/0000-0003-3479-3486)
- Zhangying Cai (ORCID: https://orcid.org/0009-0003-7810-3827)
- Long Lin (ORCID: https://orcid.org/0000-0002-7302-6557)
- Wei Pan
Institutions
- Ministry of Education (RW)
- Nanfang Hospital (CN)
- Nanfang College Guangzhou
Publication Details
- Journal
- Frontiers in Behavioral Neuroscience
- Published
- 2025-09-23
- DOI
- https://doi.org/10.3389/fnbeh.2025.1648837
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00