Changes in central and peripheral hemodynamic parameters during blood donation
Acute whole blood donation induces a mild but statistically significant decrease in peripheral SBP, accompanied by reductions in AIx and LVET, while central aortic blood pressure and vascular stiffness remain unchanged. These findings indicate that healthy individuals exhibit immediate adaptive mechanisms that preserve central cardiovascular stability in response to mild volume depletion. The results support the overall hemodynamic tolerability of blood donation and provide insight into the transient vascular and cardiac adaptations elicited by acute blood loss.
Authors
- Gökhan Yücel (ORCID: https://orcid.org/0000-0002-1803-2663)
- Bernhard K. Krämer (ORCID: https://orcid.org/0000-0002-1718-2918)
- Sabine Käyser (ORCID: https://orcid.org/0000-0003-3796-8843)
- G. Schumacher (ORCID: https://orcid.org/0000-0001-9459-1777)
- Anna Hohneck (ORCID: https://orcid.org/0000-0002-7629-2770)
- Katrin Schulz (ORCID: https://orcid.org/0000-0001-9608-0882)
- Babak Yazdani (ORCID: https://orcid.org/0000-0001-9222-8958)
- Daniel Duerschmied (ORCID: https://orcid.org/0000-0001-5249-4012)
- Behnam Shaygi
- Janine Poschauko
Institutions
- Heidelberg University (DE)
- London North West Healthcare NHS Trust (GB)
- German Red Cross (DE)
- University Hospital Heidelberg (DE)
- Klinikum Braunschweig (DE)
- German Centre for Cardiovascular Research (DE)
- University Medical Centre Mannheim (DE)
- Johannes Wesling Klinikum Minden (DE)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-09-23
- DOI
- https://doi.org/10.3389/fcvm.2025.1628366
- Citations
- 1
- Primary Topic
- Blood donation and transfusion practices
- Type
- article
- Field-Weighted Citation Impact
- 2.76