Early Activation of the Complement System After Brain Death in Clinical Kidney Donation and Transplantation
The complement system is already activated in BD donors early on during donor management. Prolonged BD duration was associated with reduced systemic complement activation. Increased systemic and local complement activation appears to negatively impact short-term kidney function.
Authors
- Daniëlle J. van Gijlswijk‐Janssen
- Mieke F. van Essen (ORCID: https://orcid.org/0000-0002-1370-2963)
- Sandra W. van der Kooij
- John F. Mulvey (ORCID: https://orcid.org/0000-0003-3843-2442)
- Maria Letizia Lo Faro (ORCID: https://orcid.org/0000-0003-3846-0101)
- Laura Knijff (ORCID: https://orcid.org/0000-0001-7923-5379)
- Cees van Kooten (ORCID: https://orcid.org/0000-0002-6257-0899)
- Rutger J. Ploeg
Institutions
- Leiden University Medical Center (NL)
- Nuffield Orthopaedic Centre (GB)
- University of Oxford (GB)
Publication Details
- Journal
- Transplantation
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1097/tp.0000000000005520
- Citations
- 1
- Primary Topic
- Complement system in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.80