Cognition, FDG metabolism, and amyloid accumulation in relation to intracranial arachnoid cysts
In an elderly population of 2292 individuals referred for PET scans under dementia evaluation, 21(1%) had an intracranial AC ≥ 2 cm. Amyloid accumulation and neuropsychological symptoms did not correlate well with cyst localization; a few cases had indication of crossed cerebellar diaschisis on FDG scans. AC are not usually explanatory of cognitive decline in a population investigated for dementia.
Authors
- Jette Stokholm Pedersen
- Ian G. Law (ORCID: https://orcid.org/0000-0001-9644-7496)
- Tiit Illimar Mathiesen (ORCID: https://orcid.org/0000-0001-9463-1919)
- Victoria Emilie Neesgaard
- Steen Gregers Hasselbalch (ORCID: https://orcid.org/0000-0003-4750-4911)
- Frantz Rom Poulsen (ORCID: https://orcid.org/0000-0001-5715-6901)
- Johanne Asperud Thomsen
Institutions
- University of Southern Denmark (DK)
- Odense University Hospital (DK)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Karolinska Institutet (SE)
- North Denmark Region (DK)
Publication Details
- Journal
- Journal of Neurology
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1007/s00415-025-13299-3
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Lundbeckfonden
- H. Lundbeck A/S