Comparative effects of 2 Hz vs. 100 Hz transcutaneous electrical nerve stimulation on upper limb motor function post-stroke: design and rationale for a randomized trial

This trial is, to our knowledge, among the first randomized head-to-head comparisons of low- vs. high-frequency TENS for post-stroke upper-limb rehabilitation. Its findings are expected to clarify frequency-dependent effects, narrow the plausible range of effective parameters, and provide evidence to inform clinical guidelines and future rehabilitation strategies.