Long‐term efficacy of rituximab versus intravenous cyclophosphamide for severe ANCA‐associated vasculitis in multicenter REVEAL cohort study
RTX demonstrated superior efficacy in improving survival and achieving GC remission, with fewer infection-related deaths compared to IVCY in patients with severe AAV. These findings reveal the efficacy and safety of RTX as a remission induction therapy in real-world Japanese clinical practice.
Authors
- Naoko Ito (ORCID: https://orcid.org/0009-0009-2536-6571)
- Yohei Fujiki
- Mikihito Shoji
- Hirofumi Miyake (ORCID: https://orcid.org/0000-0001-5655-6356)
- Mochammad Hatta (ORCID: https://orcid.org/0000-0002-8456-4203)
- Shogo Matsuda (ORCID: https://orcid.org/0000-0003-0023-3616)
- Tsuneyasu Yoshida (ORCID: https://orcid.org/0000-0003-3114-8959)
- Motomu Hashimoto (ORCID: https://orcid.org/0000-0002-9241-060X)
- Tohru Takeuchi (ORCID: https://orcid.org/0000-0002-0065-929X)
- Tomoki Taniguchi (ORCID: https://orcid.org/0000-0003-0244-6826)
- Ryosuke Hiwa (ORCID: https://orcid.org/0000-0001-6968-5712)
- Mayu Shiomi (ORCID: https://orcid.org/0009-0008-8992-1805)
- Ayana Okazaki
- Takuya Kotani (ORCID: https://orcid.org/0000-0003-2190-0780)
- Daisuke Nishioka (ORCID: https://orcid.org/0000-0002-3116-1195)
- Wataru Yamamoto (ORCID: https://orcid.org/0000-0002-0810-4221)
- Ryu Watanabe (ORCID: https://orcid.org/0000-0002-1089-5296)
- Yuichi Masuda
Institutions
- Kyoto University (JP)
- Tenri Hospital (JP)
- Kurashiki Central Hospital (JP)
- Yodogawa Christian Hospital (JP)
- Tokyo Metropolitan University (JP)
- Osaka University of Pharmaceutical Sciences (JP)
Publication Details
- Journal
- Journal of Internal Medicine
- Published
- 2025-09-22
- DOI
- https://doi.org/10.1111/joim.70024
- Citations
- 2
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 3.04