Targeting ANGPTL4 improves Treg/Th17 cell imbalance and alleviates inflammation in allergic rhinitis by suppressing the Notch signaling pathway
This paper provides evidence that the ANGPTL4 knockdown shows significant therapeutic effects on AR by improving the Treg/Th17 cell balancing, effects achieved, at least in part, by blocking the Notch signaling pathway.
Authors
- He Li (ORCID: https://orcid.org/0000-0003-0927-7666)
- Yuming Wang (ORCID: https://orcid.org/0000-0003-2310-1456)
- Yu Sun
- Xiuli Han
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1186/s40001-025-03049-6
- Citations
- 1
- Primary Topic
- Lipid metabolism and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Natural Science Foundation of Shandong Province