Assessing B19V epidemiology and viremia dynamics in plasma donors: A comprehensive analysis
The re-emergence of B19V with high positivity rates highlights the relevance of donation testing for plasma. During the month from infection onset, B19V DNAemia correlates well with the measured infectious titer. B19V infectivity in plasma disappears within a month while DNA can persist in the plasma in absence of detectable infectivity, likely due to the immune response as characterized by the immunological markers.
Authors
- Jonas Sieber (ORCID: https://orcid.org/0000-0002-4325-4444)
- Joyce Castaneda
- Remo Leisi
- Denis Klochkov
- M. Natali (ORCID: https://orcid.org/0000-0002-7736-983X)
- Martin Wälti
- Susanne Mie Rohde
- Björn Keiner
- Eleonora Widmer
- Rick Alexander
- Kelley Hyatt
- Eva Quinley
- Michael Schiffer
- Adrian Sanden
- Christoph Zürcher
Institutions
- Plasma Technology (United States) (US)
- CSL (Switzerland) (CH)
Publication Details
- Journal
- Journal of Clinical Virology
- Published
- 2025-09-23
- DOI
- https://doi.org/10.1016/j.jcv.2025.105873
- Citations
- 1
- Primary Topic
- Parvovirus B19 Infection Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.40