A Case Report and Global Perspective on Fusarium Superficial Keratitis in the Pediatric Population

Fungal keratitis is a major cause of corneal blindness in tropical regions, with Fusarium species predominating. Pediatric cases, though less common, carry a greater risk of amblyopia and long-term disability. We report a nine-year-old boy who developed Fusarium keratitis after minor ocular trauma and unsupervised corticosteroid use. Corneal scrapings showed septate hyphae, and identification confirmed <i>Fusarium solani</i> by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Treatment with topical natamycin and voriconazole led to complete healing without surgery. This case highlights the need for early recognition, rapid microbiological confirmation, and appropriate antifungal therapy in pediatric fungal keratitis, while underscoring the dangers of unsupervised corticosteroid use in endemic regions.

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Publication Details

Journal
Cureus
Published
2025-09-22
DOI
https://doi.org/10.7759/cureus.92937
Primary Topic
Ocular Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

A Case Report and Global Perspective on Fusarium Superficial Keratitis in the Pediatric Population

Siddharam S Janti, Rahul Narang, S. S. Avinash, Pravalika Rebbala et al.
Cureus
Ocular Infections and Treatments
article

A Case Report and Global Perspective on Fusarium Superficial Keratitis in the Pediatric Population

Siddharam S Janti, Rahul Narang, S. S. Avinash, Pravalika Rebbala, Shalam Nikhat Sheerin, Rajesh Kanna Kannabiran, Rahul Garg, Sree Ranjani S
article en

Abstract

Fungal keratitis is a major cause of corneal blindness in tropical regions, with Fusarium species predominating. Pediatric cases, though less common, carry a greater risk of amblyopia and long-term disability. We report a nine-year-old boy who developed Fusarium keratitis after minor ocular trauma and unsupervised corticosteroid use. Corneal scrapings showed septate hyphae, and identification confirmed <i>Fusarium solani</i> by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Treatment with topical natamycin and voriconazole led to complete healing without surgery. This case highlights the need for early recognition, rapid microbiological confirmation, and appropriate antifungal therapy in pediatric fungal keratitis, while underscoring the dangers of unsupervised corticosteroid use in endemic regions.

CureusVol. 17(9)
All India Institute of Medical Sciences (IN)
Openalex Percentile: Top 62%
Ocular Infections and Treatments
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