Cytologically non-malignant thyroid nodules with three or more high-risk genetic mutations have poor outcomes

Despite bland cytological and ultrasonographic features, these tumors exhibited aggressive behavior. The molecular profile of thyroid cancers should be considered when determining treatment, especially in cases with multiple high-risk mutations, as they may behave more aggressively than predicted by cytology or imaging alone.

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Publication Details

Journal
Endocrine Oncology
Published
2025-01-01
DOI
https://doi.org/10.1530/eo-25-0054
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Cytologically non-malignant thyroid nodules with three or more high-risk genetic mutations have poor outcomes

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Endocrine Oncology
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Cytologically non-malignant thyroid nodules with three or more high-risk genetic mutations have poor outcomes

Steven P. Hodak, Sumedha Chablani, Abraham Goldberg, Gary D. Rothberger, Kepal N. Patel, Rong Xia, Liu C
article en

Abstract

Despite bland cytological and ultrasonographic features, these tumors exhibited aggressive behavior. The molecular profile of thyroid cancers should be considered when determining treatment, especially in cases with multiple high-risk mutations, as they may behave more aggressively than predicted by cytology or imaging alone.

Endocrine OncologyVol. 5(1)
New York University (US)
Openalex Percentile: Top 65%
Thyroid Cancer Diagnosis and Treatment
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