Optimizing MRI Protocols for Brain Radiosurgery

Both MRI sequence choice and imaging time after CA administration significantly affect the apparent volume of brain metastases in SRT planning. Although SPACE and VIBE sequences enhance small lesion detection, they may also increase border blurring and inter-rater variability. Standardizing protocols to account for these factors is essential for improving delineation accuracy, reducing toxicity risk, and optimizing SRT outcomes.

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Publication Details

Journal
Investigative Radiology
Published
2025-09-22
DOI
https://doi.org/10.1097/rli.0000000000001238
Citations
1
Primary Topic
Brain Metastases and Treatment
Type
article
Field-Weighted Citation Impact
1.52
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article

Optimizing MRI Protocols for Brain Radiosurgery

Samuel Vorbach, Matthias Santer, Astrid Grams, Daniel Dejaco et al.
1 citations
Investigative Radiology
Brain Metastases and Treatment
1.52
article

Optimizing MRI Protocols for Brain Radiosurgery

Samuel Vorbach, Matthias Santer, Astrid Grams, Daniel Dejaco, Elke R. Gizewski, Christoph Birkl, Manuel Weber, Christian Kremser, Ute Ganswindt, Malik Galijašević, Johannes Kerschbaumer, Stephanie Mangesius, Julian Mangesius, Thomas Seppi, Michaela Wagner
article en
1 citations

Abstract

Both MRI sequence choice and imaging time after CA administration significantly affect the apparent volume of brain metastases in SRT planning. Although SPACE and VIBE sequences enhance small lesion detection, they may also increase border blurring and inter-rater variability. Standardizing protocols to account for these factors is essential for improving delineation accuracy, reducing toxicity risk, and optimizing SRT outcomes.

Investigative Radiology
Innsbruck Medical University (AT), Cognitive Neuroimaging Lab (FR)
Openalex Percentile: Top 14%
Brain Metastases and Treatment
1.52
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Optimizing MRI Protocols for Brain Radiosurgery — Samuel Vorbach, Matthias Santer, et al. · Investigative Radiology (2025) | TGRS Research Map | TGRS