Kaempferol Alleviates Dry Eye Disease Via Modulation of the IDH3B/CCAR2/IKBKB Axis
This study provides new insights into the therapeutic potential of KAE as a promising candidate for DED treatment, particularly regulating cell cycle and apoptosis via the IDH3B/CCAR2/IKBKB axis.
Authors
- Jiaxu Hong
- Yun Xie (ORCID: https://orcid.org/0000-0002-4341-7426)
- Sha Yang (ORCID: https://orcid.org/0000-0003-0345-5740)
- Shuyan Zhang (ORCID: https://orcid.org/0009-0004-3157-2818)
Institutions
- Shanghai Eye Disease Prevention & Treatment Center (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Longhua Hospital Shanghai University of Traditional Chinese Medicine (CN)
- Eye & ENT Hospital of Fudan University (CN)
- State Key Laboratory of Synthetic Chemistry (CN)
- Shanghai Traditional Chinese Medicine Hospital (CN)
- Children's Hospital of Fudan University (CN)
- Jiangsu Provincial Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-09-22
- DOI
- https://doi.org/10.1167/iovs.66.12.50
- Citations
- 2
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 3.76