Kinetics Of 3-Methylindole Oxidation : A Comparative Study Of Potassium Bromate And Peroxomonosuphate

The kinetic studies of oxidation of 3-Methylindole (3-MI) by peroxomonsulphate (PMS) and potassium bromate (KBrO3) have been carried out in ethanol medium. A total second order, first order each with respect to [3-MI] and [Oxidant] has been observed. The rate of the reaction was not affected by added [H+]. Variation of ionic strength (μ) had no influence on the rate. Increase of percentage of solvents decreased the rate. Absence of any polymerization indicated a no radical pathway. Activation and thermodynamic parameters have been computed. A suitable kinetic mechanism based on these observations is proposed. The product was confirmed from the IR and NMR spectral analysis. The reactivity of Potassium bromate toward 3-methylindole was found to be lower than that with Peroxomonsulpahte.