Severe hepatic steatosis contributes to liver dysfunction in non‐obese patients with insulin‐resistant diabetes mellitus after hematopoietic stem cell transplantation

Non-obese HSCT survivors with insulin-resistant DM exhibited severe hepatic fat accumulation and progression of liver fibrosis attributable to lipodystrophy. FibroScan may have potential utility for monitoring liver health in this population.

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Publication Details

Journal
Pediatrics International
Published
2025-01-01
DOI
https://doi.org/10.1111/ped.70192
Primary Topic
Hematopoietic Stem Cell Transplantation
Type
article
Field-Weighted Citation Impact
0.00
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Severe hepatic steatosis contributes to liver dysfunction in non‐obese patients with insulin‐resistant diabetes mellitus after hematopoietic stem cell transplantation

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Severe hepatic steatosis contributes to liver dysfunction in non‐obese patients with insulin‐resistant diabetes mellitus after hematopoietic stem cell transplantation

Takeshi Isoda, Fukiko Kitahata, Kei Takasawa, Ryuichi Nakagawa, Satoshi Okada, Miyako Murakawa, Ryosei Iemura, Haruki Yamano, Tomohiro Morio, Reiko Kagawa, Yoko Saito, Kenichi Kashimada, Akito Sutani, Shigeru Takishima, Maki Gau, Takahiro Kamiya, Eriko Adachi, T Yamauchi
article en

Abstract

Non-obese HSCT survivors with insulin-resistant DM exhibited severe hepatic fat accumulation and progression of liver fibrosis attributable to lipodystrophy. FibroScan may have potential utility for monitoring liver health in this population.

Pediatrics InternationalVol. 67(1)
Hiroshima University (JP), Tokyo Metropolitan Institute of Medical Science (JP), University of Tokyo Hospital (JP), National Center For Child Health and Development (JP), The University of Tokyo (JP)
Openalex Percentile: Top 66%
Hematopoietic Stem Cell Transplantation
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