Polymyxin B Hemoperfusion for Patients With Septic Shock Requiring High-Dose Norepinephrine: A Multicenter Prospective Cohort Study
PMX-HP was not associated with the 28-day mortality improvement but was associated with higher MAP and lower vasopressor use for 8-32 hours of admission. Our findings suggested that PMX-HP requires careful adaptation.
Authors
- Tsuyoshi Suzuki (ORCID: https://orcid.org/0009-0009-8355-0756)
- Kazunori Fukushima (ORCID: https://orcid.org/0000-0003-2207-4011)
- Kyohei Miyamoto (ORCID: https://orcid.org/0000-0001-5473-2731)
- Minori Kinjo
- Yu Kawazoe (ORCID: https://orcid.org/0000-0003-4471-4788)
- Tasuku Hanajima (ORCID: https://orcid.org/0000-0003-1428-4043)
- Tetsuya Sato (ORCID: https://orcid.org/0000-0002-1373-5810)
- Jun‐ichi Maruyama (ORCID: https://orcid.org/0000-0002-5318-5366)
- Satoru Murata (ORCID: https://orcid.org/0000-0001-7772-0821)
- Michihito Kyo (ORCID: https://orcid.org/0000-0002-2559-6440)
- Yukitoshi Toyoda
- Takeshi Morimoto (ORCID: https://orcid.org/0000-0002-6844-739X)
- Noriko Miyagawa (ORCID: https://orcid.org/0000-0002-7206-5829)
- Tomoya Okazaki (ORCID: https://orcid.org/0000-0002-0540-8772)
- Takuya Kimura
- Hiroshi Matsuura (ORCID: https://orcid.org/0000-0002-8618-0385)
- Hitoshi Yamamura (ORCID: https://orcid.org/0000-0003-1903-4879)
- Toshihiro Sakurai (ORCID: https://orcid.org/0009-0001-4480-7258)
- Gaku Takahashi (ORCID: https://orcid.org/0000-0002-5947-6295)
- Masaki Takahashi (ORCID: https://orcid.org/0000-0002-3615-2132)
- Yoshinori Ohta
Institutions
- Hiroshima University (JP)
- Fukushima Medical University (JP)
- Gunma University (JP)
- Iwate Medical University (JP)
- Wakayama Medical University (JP)
- Hokkaido University (JP)
- Kyoto Medical Center (JP)
- Hiratsuka City Hospital (JP)
- Fukuoka University Hospital (JP)
- Tohoku University Hospital (JP)
- Sendai Medical Center (JP)
- Osaka Prefectural Institute of Public Health (JP)
- Saiseikai Utsunomiya hospital (JP)
- Osaka Hospital (JP)
- Shizuoka General Hospital (JP)
- Kagawa University Hospital (JP)
- Kumamoto Medical Center (JP)
- Ehime University (JP)
- Nara Prefecture General Medical Center (JP)
- Nara Medical University (JP)
- Hyogo University (JP)
Publication Details
- Journal
- Critical Care Explorations
- Published
- 2025-09-22
- DOI
- https://doi.org/10.1097/cce.0000000000001320
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00