Concordance between initial GeneXpert MTB/RIF results and follow-up diagnostic testing in patients treated for multidrug-resistant tuberculosis in Lusaka, Zambia

false positive results for rifampicin susceptibility on GeneXpert MTB/RIF appear to be common in Lusaka, Zambia, especially in patients with very low bacillary loads on the initial test. Repeat testing to confirm MDR-TB prior to initiation of treatment can be considered in this group.

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Publication Details

Journal
Pan African Medical Journal
Published
2025-01-01
DOI
https://doi.org/10.11604/pamj.2025.52.33.43309
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
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article

Concordance between initial GeneXpert MTB/RIF results and follow-up diagnostic testing in patients treated for multidrug-resistant tuberculosis in Lusaka, Zambia

Kondwelani Mateyo, Thijs W. Hoffman, Angel Mubanga, Maurice Mwansa
Pan African Medical Journal
Tuberculosis Research and Epidemiology
article

Concordance between initial GeneXpert MTB/RIF results and follow-up diagnostic testing in patients treated for multidrug-resistant tuberculosis in Lusaka, Zambia

Kondwelani Mateyo, Thijs W. Hoffman, Angel Mubanga, Maurice Mwansa
article en

Abstract

false positive results for rifampicin susceptibility on GeneXpert MTB/RIF appear to be common in Lusaka, Zambia, especially in patients with very low bacillary loads on the initial test. Repeat testing to confirm MDR-TB prior to initiation of treatment can be considered in this group.

Pan African Medical JournalVol. 52
University Teaching Hospital (ZM)
Openalex Percentile: Top 69%
Tuberculosis Research and Epidemiology
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