Bevacizumab-Associated Enterocutaneous Fistula: A Case Report and Management Review

Enterocutaneous fistula (ECF) formation is a rare but severe complication of bevacizumab therapy. This case report documents the first known patient to develop both an ECF and a colovaginal fistula following bevacizumab treatment for recurrent cervical cancer without prior radiation therapy. A comprehensive literature review of current and nutritional management guidelines, in the context of this patient's complex condition, highlights the need for refined risk stratification and management frameworks. This report aims to contribute to the evolving understanding of bevacizumab's adverse effects and inform future therapeutic decision-making.