Heterologous DNA–Adenovirus Prime–Boost Strategy Expressing Bluetongue Virus VP2 and VP7 Proteins Protects Against Virulent Challenge
These findings highlight the potential of heterologous DNA-adenovirus vaccination as an effective DIVA-compatible strategy for BTV control. By inducing strong and protective immune responses, this approach could improve disease surveillance and management, ultimately reducing the impact of BTV on livestock industries.
Authors
- José M. Rojas (ORCID: https://orcid.org/0000-0002-4055-3967)
- Noemı́ Sevilla (ORCID: https://orcid.org/0000-0003-0118-0376)
- Ana Belén Carlón
- Vicente Larraga (ORCID: https://orcid.org/0000-0003-1260-7400)
- Jaime Larraga (ORCID: https://orcid.org/0000-0001-7293-7239)
- Andrés Louloudes-Lázaro (ORCID: https://orcid.org/0000-0001-6263-8606)
- Pedro J. Alcolea (ORCID: https://orcid.org/0000-0002-0729-8941)
- Pablo Nogales‐Altozano
- Verónica Martı́n (ORCID: https://orcid.org/0000-0003-1486-1656)
- Ana Alonso
- Laro Gómez‐Marcos
- Alicia Rivera-Rodríguez
Institutions
- Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (ES)
- Centro de Investigaciones Biológicas Margarita Salas (ES)
Publication Details
- Journal
- Vaccines
- Published
- 2025-09-22
- DOI
- https://doi.org/10.3390/vaccines13090991
- Citations
- 1
- Primary Topic
- Vector-Borne Animal Diseases
- Type
- article
- Field-Weighted Citation Impact
- 3.03