Etiological spectrum and diagnostic features of lymphadenopathy in People Living with HIV in French Guiana: A 17-years multicenter retrospective case series
For the last 17 years, opportunistic infections represented 53% of the causes of lymphadenopathy among PLHIV. Histoplasmosis, already recognized as the first AIDS-defining condition and first cause of AIDS-related deaths in French Guiana, is also the first cause of lymphadenopathy in PLHIV, ahead of tuberculosis and reactive lymphadenopathy. The CD4 count and the size of the lymph nodes appear to be the most important factors in the diagnostic process and should lead to a quick lymph node analysis in these patients.
Authors
- M. Bourne-Watrin (ORCID: https://orcid.org/0000-0003-2216-9715)
- Pierre Couppié (ORCID: https://orcid.org/0000-0002-4213-2867)
- Antoine Adenis (ORCID: https://orcid.org/0000-0003-4000-4981)
- Mathieu Nacher (ORCID: https://orcid.org/0000-0001-9397-3204)
- Kinan Drak Alsibai (ORCID: https://orcid.org/0000-0001-5975-2627)
- Ugo Françoise (ORCID: https://orcid.org/0000-0002-3239-5145)
- Dufens Pierre Louis
- Sophie Alexandra Baron
- F. Djossou (ORCID: https://orcid.org/0000-0002-6761-0511)
- L. Epelboin
Institutions
- Center for Infection and Immunity of Lille (FR)
- Institut Pasteur de la Guyane (GF)
- Centre Hospitalier Andrée Rosemon (GF)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2025-09-22
- DOI
- https://doi.org/10.1371/journal.pntd.0013558
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00