Modelling the relative contribution of infection, routine vaccination and supplementary immunisation activities to measles seroconversion in Kenyan Children
Optimizing routine coverage timing and uptake is crucial for reducing SIAs dependence and measles susceptibility. A 10% MCV1 coverage increase could have halved susceptibility and lessened SIA demand, highlighting the potential of minor improvements in coverage to alleviate measles and reduce costly SIAs.
Authors
- Gaby P. Smits (ORCID: https://orcid.org/0000-0003-4890-0940)
- John Ojal (ORCID: https://orcid.org/0000-0002-3010-1158)
- Caroline Mburu (ORCID: https://orcid.org/0000-0001-6362-3537)
- E. Wangeci Kagucia (ORCID: https://orcid.org/0000-0002-4481-8889)
- Rose Ombati (ORCID: https://orcid.org/0000-0002-2649-7284)
- Boniface Karia (ORCID: https://orcid.org/0000-0003-0875-8935)
- Stefan Flasche (ORCID: https://orcid.org/0000-0002-5808-2606)
- Rose Selim (ORCID: https://orcid.org/0000-0001-6969-167X)
- Pieter G. M. van Gageldonk (ORCID: https://orcid.org/0000-0003-2753-9674)
- Fiona R.M. van der Klis (ORCID: https://orcid.org/0000-0002-6759-3539)
- James Tuju (ORCID: https://orcid.org/0000-0002-0624-1791)
- Antipa Sigilai (ORCID: https://orcid.org/0000-0003-1185-3677)
- Donald Akech (ORCID: https://orcid.org/0000-0002-2637-3708)
- Ifedayo Adetifa (ORCID: https://orcid.org/0000-0003-2556-9407)
- Anthony Scott
Institutions
- Kenya Medical Research Institute (KE)
- London School of Hygiene & Tropical Medicine (GB)
- National Institute for Public Health and the Environment (NL)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- PLoS Computational Biology
- Published
- 2025-09-22
- DOI
- https://doi.org/10.1371/journal.pcbi.1013531
- Primary Topic
- Virology and Viral Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00