Bile duct stenosis in hepatolithiasis: a detailed characteristics and predictors for stone clearance

Our aim is to identify the prognostic factors for post-operative residual stone. Methods. Our retrospective study recruited 201 participants with hepatolithiasis and bile duct stenosis who underwent choledochoscopic lithotripsy with or without parenchyma incision and hepatic resection in Department of Hepatobiliary surgery, VietDuc University hospital, Hanoi, Vietnam from 1/2018 to 12/2020. Demographic information, clinical features, laboratory results, type of operation, bile duct stenosis characteristics (site, number, severity) were collected. Our primary endpoint was the post-operative stone clearance rate. Results. 82.6% had one stricture site, 49.8% had a severe stricture. The stone clearance rate after CEHL was 43.2, and combined hepatectomy/parenchymal incision was 75.3%. Multiple approaches and type of intrahepatic stone are two associated factors for residual stone. Conclusion. Choledoscopy is a valuable tool in finding gallstones and acquiring bile duct characteristics. Hepatectomy and parenchymal incision, along with choledoscopic lithotripsy, is a safe and effective method for increasing the clearance rate for hepatolithiasis and bile duct stricture. Comprehensive and aggressive treatment is needed in complicated intrahepatic stones.

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Journal
Annaly khirurgicheskoy gepatologii = Annals of HPB surgery
Published
2025-09-22
DOI
https://doi.org/10.16931/1995-5464.2025-3-99-106
Primary Topic
Gallbladder and Bile Duct Disorders
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article
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article

Bile duct stenosis in hepatolithiasis: a detailed characteristics and predictors for stone clearance

Thanh Khiem Nguyen, Lan Nguyen, Đang Hai
Annaly khirurgicheskoy gepatologii = Annals of HPB surgery
Gallbladder and Bile Duct Disorders
article

Bile duct stenosis in hepatolithiasis: a detailed characteristics and predictors for stone clearance

Thanh Khiem Nguyen, Lan Nguyen, Đang Hai
article en

Abstract

Our aim is to identify the prognostic factors for post-operative residual stone. Methods. Our retrospective study recruited 201 participants with hepatolithiasis and bile duct stenosis who underwent choledochoscopic lithotripsy with or without parenchyma incision and hepatic resection in Department of Hepatobiliary surgery, VietDuc University hospital, Hanoi, Vietnam from 1/2018 to 12/2020. Demographic information, clinical features, laboratory results, type of operation, bile duct stenosis characteristics (site, number, severity) were collected. Our primary endpoint was the post-operative stone clearance rate. Results. 82.6% had one stricture site, 49.8% had a severe stricture. The stone clearance rate after CEHL was 43.2, and combined hepatectomy/parenchymal incision was 75.3%. Multiple approaches and type of intrahepatic stone are two associated factors for residual stone. Conclusion. Choledoscopy is a valuable tool in finding gallstones and acquiring bile duct characteristics. Hepatectomy and parenchymal incision, along with choledoscopic lithotripsy, is a safe and effective method for increasing the clearance rate for hepatolithiasis and bile duct stricture. Comprehensive and aggressive treatment is needed in complicated intrahepatic stones.

Annaly khirurgicheskoy gepatologii = Annals of HPB surgeryVol. 30(3)
Bạch Mai Hospital (VN), Viet Duc Hospital (VN)
Openalex Percentile: Top 63%
Gallbladder and Bile Duct Disorders
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Bile duct stenosis in hepatolithiasis: a detailed characteristics and predictors for stone clearance — Thanh Khiem Nguyen, Lan Nguyen, et al. · Annaly khirurgicheskoy gepatologii = Annals of HPB surgery (2025) | TGRS Research Map | TGRS