Elevated serum apelin levels in breast cancer patients: A potential biomarker with limited histopathological correlations
Our findings suggest a potential role for serum apelin in breast cancer pathogenesis or progression. The high discriminative ability of serum apelin indicates its promise as a biomarker for breast cancer detection. However, the lack of association between serum apelin levels and specific clinicopathological features suggests a limited prognostic value and a complex role in breast cancer biology that warrants further investigation.
Authors
- Adel Soltanizadeh (ORCID: https://orcid.org/0000-0002-5963-2139)
- Mohammad Shabani (ORCID: https://orcid.org/0000-0002-2082-5849)
- Ali Karamoozian (ORCID: https://orcid.org/0000-0002-1677-2852)
- Elham Jafari (ORCID: https://orcid.org/0000-0001-9240-9177)
- Mehran Ilaghi (ORCID: https://orcid.org/0000-0002-6674-5406)
- Vahid Moazed (ORCID: https://orcid.org/0000-0003-0525-4539)
- Ali Zarei Mahmoudabadi (ORCID: https://orcid.org/0000-0002-5347-2082)
- Sarah Aflatoonian
- Aliasghar Tirgar
- Yasaman Zamanian
Institutions
- Kerman University of Medical Sciences (IR)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-09-22
- DOI
- https://doi.org/10.3389/fonc.2025.1513693
- Primary Topic
- Apelin-related biomedical research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Kerman University of Medical Sciences