Machine Learning and Shapley Additive Explanations Value Integration for Predicting the Prognostic of Anti-N-Methyl-D-Aspartate Receptor Encephalitis: Model Development and Evaluation Study

We developed and validated an interpretable RF-based prognostic model for NMDAR encephalitis. The web-deployed tool enables real-time risk stratification, facilitating clinical decision-making and personalized therapeutic interventions for clinicians.

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Publication Details

Journal
JMIR Medical Informatics
Published
2025-09-22
DOI
https://doi.org/10.2196/75020
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
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article

Machine Learning and Shapley Additive Explanations Value Integration for Predicting the Prognostic of Anti-N-Methyl-D-Aspartate Receptor Encephalitis: Model Development and Evaluation Study

Y Wang, Haotian Wu, Jian Gu, Jia Wang et al.
JMIR Medical Informatics
Autoimmune Neurological Disorders and Treatments
article

Machine Learning and Shapley Additive Explanations Value Integration for Predicting the Prognostic of Anti-N-Methyl-D-Aspartate Receptor Encephalitis: Model Development and Evaluation Study

Y Wang, Haotian Wu, Jian Gu, Jia Wang, HANQIN CAI
article en

Abstract

We developed and validated an interpretable RF-based prognostic model for NMDAR encephalitis. The web-deployed tool enables real-time risk stratification, facilitating clinical decision-making and personalized therapeutic interventions for clinicians.

JMIR Medical InformaticsVol. 13
Sun Yat-sen University (CN), Third Affiliated Hospital of Sun Yat-sen University (CN)
Openalex Percentile: Top 63%
Autoimmune Neurological Disorders and Treatments
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