18F-FDG and 68Ga-FAPI PET/CT Imaging in a Rare Case of Lymphoma With Pericardial and Renal Involvement

In lymphoma, 18F-FDG PET/CT is commonly used for diagnosis; however, in this case, 68Ga-FAPI-46 PET/CT also demonstrated significant uptake, suggesting its potential in detecting lymphoma-related desmoplastic reactions. The patient, presenting with pericardial effusion and elevated inflammatory markers, was ultimately diagnosed with diffuse large B-cell lymphoma (DLBCL) through histopathology. This case highlights the complementary role of 68Ga-FAPI PET/CT alongside 18F-FDG PET/CT in lymphoma diagnosis, offering additional insights into tumor characteristics and prognosis.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2025-09-19
DOI
https://doi.org/10.1097/rlu.0000000000006122
Primary Topic
Peptidase Inhibition and Analysis
Type
article
Field-Weighted Citation Impact
0.00
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article

18F-FDG and 68Ga-FAPI PET/CT Imaging in a Rare Case of Lymphoma With Pericardial and Renal Involvement

Anuradha Sekaran, Sachin Yalagudri, Mohan Roop Jayanthi, Harini Koorma
Clinical Nuclear Medicine
Peptidase Inhibition and Analysis
article

18F-FDG and 68Ga-FAPI PET/CT Imaging in a Rare Case of Lymphoma With Pericardial and Renal Involvement

Anuradha Sekaran, Sachin Yalagudri, Mohan Roop Jayanthi, Harini Koorma
article en

Abstract

In lymphoma, 18F-FDG PET/CT is commonly used for diagnosis; however, in this case, 68Ga-FAPI-46 PET/CT also demonstrated significant uptake, suggesting its potential in detecting lymphoma-related desmoplastic reactions. The patient, presenting with pericardial effusion and elevated inflammatory markers, was ultimately diagnosed with diffuse large B-cell lymphoma (DLBCL) through histopathology. This case highlights the complementary role of 68Ga-FAPI PET/CT alongside 18F-FDG PET/CT in lymphoma diagnosis, offering additional insights into tumor characteristics and prognosis.

Clinical Nuclear Medicine
Openalex Percentile: Top 65%
Peptidase Inhibition and Analysis
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