Enterocytozoon bieneusi infection disrupts bile acid metabolism in the wild rodent gut microbiota: adaptive shifts in microbial metabolism and community structure
Our findings highlight the intricate interconnections between gut microbial functions, BA metabolism, and pathogen interactions. The absence of 7β-HSDH in laboratory mice underscores wild rodents as potentially more suitable models for BA research. These results open new avenues for understanding microbiome-driven host adaptation and health.
Authors
- Bei-Ni Chen
- Jixin Zhao (ORCID: https://orcid.org/0000-0002-1035-8810)
- Hany M. Elsheikha (ORCID: https://orcid.org/0000-0003-3303-930X)
- Quan Zhao
- Xing Yang (ORCID: https://orcid.org/0000-0003-0588-8371)
- Jianming Li (ORCID: https://orcid.org/0000-0003-3231-0778)
- Xiao‐Xuan Zhang (ORCID: https://orcid.org/0000-0002-9470-2892)
- Ziyu Zhao (ORCID: https://orcid.org/0000-0001-8321-1193)
- He Ma (ORCID: https://orcid.org/0000-0003-0230-1272)
- Ya Qin (ORCID: https://orcid.org/0000-0002-9338-1345)
- Kai-Meng Shang
- Yongjie Wei
- Hailong Yu
Institutions
- Loughborough University (GB)
- Qingdao Agricultural University (CN)
- Jilin Agricultural University (CN)
- Changchun University (CN)
- Dali University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-09-22
- DOI
- https://doi.org/10.3389/fcimb.2025.1647377
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81