Nomogram for predicting pathological complete response to neoadjuvant chemoimmunotherapy in patients with resectable non-small cell lung cancer
This nomogram, derived from routine clinical data, predicts pCR after neoadjuvant chemoimmunotherapy in NSCLC, offering a tool for thoracic surgeons to optimize treatment and surgical planning, despite its modest discriminative power, by serving as a complementary aid in resource-limited settings where biomarkers may not be readily available. External validation in larger, multi-center cohorts is essential.
Authors
- Zhilin Sui
- Chunguang Wang (ORCID: https://orcid.org/0000-0001-5569-321X)
- Songhua Cai (ORCID: https://orcid.org/0000-0003-3839-2030)
- Zhentao Yu (ORCID: https://orcid.org/0000-0002-5785-8492)
- Wenyi Liu (ORCID: https://orcid.org/0000-0003-2069-0865)
- Ran Jia (ORCID: https://orcid.org/0000-0001-9895-5734)
- Baihua Zhang (ORCID: https://orcid.org/0000-0001-9712-9043)
- Youjun Deng (ORCID: https://orcid.org/0000-0002-2904-6438)
Institutions
- Fujian Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Hunan Cancer Hospital (CN)
- Union Hospital (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-09-22
- DOI
- https://doi.org/10.3389/fcell.2025.1679782
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00