ZDHHC5 as a central regulator in a palmitoylation-associated prognostic model for lung adenocarcinoma: insights from pan-cancer and experimental analyses
A prognostic model based on palmitoylation-related genes offers a valuable tool for survival prediction and the development of personalized treatment strategies in LUAD. ZDHHC5, a key gene related to palmitoylation, demonstrates potential as both a therapeutic target and a prognostic marker for LUAD and other cancers.
Authors
- Haipeng Xu (ORCID: https://orcid.org/0000-0001-7511-4991)
- Renji Liang
- Junfan Pan (ORCID: https://orcid.org/0000-0002-6141-3883)
- Qihong Pan
- Jiancheng Li (ORCID: https://orcid.org/0000-0003-2148-9872)
- Sixuan Wu (ORCID: https://orcid.org/0000-0001-7690-723X)
- Yuanbin Tang (ORCID: https://orcid.org/0009-0007-0124-6319)
- Yaqin Zheng (ORCID: https://orcid.org/0000-0002-8189-7707)
Institutions
- Fujian Medical University (CN)
- First Affiliated Hospital of University of South China (CN)
- Fujian Provincial Cancer Hospital (CN)
- Fuzhou University (CN)
- University of South China (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-22
- DOI
- https://doi.org/10.3389/fimmu.2025.1643112
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00