Case Report: A complex case of an adolescent female with comorbid borderline personality disorder and autism spectrum disorder

Diagnosing borderline personality disorder (BPD) and autism spectrum disorder (ASD) in adolescent females presents significant challenges due to the overlap in their symptomatology. Both conditions share features such as emotional dysregulation, impulsivity, and difficulties in interpersonal relationships, making differentiation crucial yet difficult. This case report examines an adolescent female with co-occurring BPD and ASD, emphasizing the complexities of distinguishing between the two. It explores the role of developmental history, behavioral patterns, and neurobiological factors in forming a precise diagnosis. Additionally, the report highlights the impact of comorbid conditions like depression and anxiety, which frequently accompany both BPD and ASD, further complicating the diagnostic process. By focusing on this case, we underscore the importance of a thorough, multidimensional diagnostic approach to ensure accurate identification and treatment. The case serves as a reminder of the need for heightened awareness of how BPD and ASD can present in females and advocates for more nuanced diagnostic tools and tailored interventions to improve clinical outcomes for this population.

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Publication Details

Journal
Frontiers in Psychiatry
Published
2025-09-22
DOI
https://doi.org/10.3389/fpsyt.2025.1681412
Primary Topic
Autism Spectrum Disorder Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Case Report: A complex case of an adolescent female with comorbid borderline personality disorder and autism spectrum disorder

Hojka Gregorič Kumperščak, Ajda Demšar, Sara Močnik
Frontiers in Psychiatry
Autism Spectrum Disorder Research
article

Case Report: A complex case of an adolescent female with comorbid borderline personality disorder and autism spectrum disorder

Hojka Gregorič Kumperščak, Ajda Demšar, Sara Močnik
article en

Abstract

Diagnosing borderline personality disorder (BPD) and autism spectrum disorder (ASD) in adolescent females presents significant challenges due to the overlap in their symptomatology. Both conditions share features such as emotional dysregulation, impulsivity, and difficulties in interpersonal relationships, making differentiation crucial yet difficult. This case report examines an adolescent female with co-occurring BPD and ASD, emphasizing the complexities of distinguishing between the two. It explores the role of developmental history, behavioral patterns, and neurobiological factors in forming a precise diagnosis. Additionally, the report highlights the impact of comorbid conditions like depression and anxiety, which frequently accompany both BPD and ASD, further complicating the diagnostic process. By focusing on this case, we underscore the importance of a thorough, multidimensional diagnostic approach to ensure accurate identification and treatment. The case serves as a reminder of the need for heightened awareness of how BPD and ASD can present in females and advocates for more nuanced diagnostic tools and tailored interventions to improve clinical outcomes for this population.

Frontiers in PsychiatryVol. 16
University of Maribor (SI), University Clinical Centre Maribor (SI)
Openalex Percentile: Top 74%
Autism Spectrum Disorder Research
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Case Report: A complex case of an adolescent female with comorbid borderline personality disorder and autism spectrum disorder — Hojka Gregorič Kumperščak, Ajda Demšar, et al. · Frontiers in Psychiatry (2025) | TGRS Research Map | TGRS