A novel broad-spectrum lytic phage vB_EcoM_P3322: isolation, characterization, and therapeutic potential against avian pathogenic Escherichia coli
In summary, vB_EcoM_P3322 displays broad-spectrum lytic activity, robust environmental stability, potent antibacterial efficacy both in vitro and in vivo, and a safe genomic profile. These attributes support its potential as a novel biocontrol agent for managing APEC infections in poultry farming.
Authors
- Xueqin Lan
- Mingshuai Chen (ORCID: https://orcid.org/0000-0001-9663-7441)
- Yuan Tian (ORCID: https://orcid.org/0000-0001-7355-4096)
- Wei Zhang (ORCID: https://orcid.org/0000-0001-9004-1161)
- Ying Huang (ORCID: https://orcid.org/0000-0001-9816-4713)
- Jinxin Xie (ORCID: https://orcid.org/0000-0003-4772-7162)
- Panpan Tong (ORCID: https://orcid.org/0000-0002-0027-4437)
- Zhanqiang Su
- Yixin Bai
- Wenjie Jin (ORCID: https://orcid.org/0000-0001-5961-4937)
- Mengfei Zhang
- Mingyang Geng (ORCID: https://orcid.org/0000-0001-9020-4581)
- Qijiao Zang
- Gulina Aishan
Institutions
- Nanjing Agricultural University (CN)
- Xinjiang Agricultural University (CN)
- Research Institute of Animal Husbandry (MN)
- Xinjiang University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-09-22
- DOI
- https://doi.org/10.3389/fcimb.2025.1645263
- Citations
- 1
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- China Postdoctoral Science Foundation
- Xinjiang Agricultural University
- Natural Science Foundation of Xinjiang