SLFN11 expression correlates with immune microenvironment and predicts prognosis in melanoma

These findings provide evidence that SLFN11 is associated with immune microenvironment changes in melanoma, correlates with favorable prognosis, and may be linked to immunotherapy response, supporting its potential as a candidate biomarker and therapeutic target for further investigation.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-09-22
DOI
https://doi.org/10.3389/fimmu.2025.1607056
Citations
1
Primary Topic
PARP inhibition in cancer therapy
Type
article
Field-Weighted Citation Impact
1.05
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article

SLFN11 expression correlates with immune microenvironment and predicts prognosis in melanoma

Huancheng Zeng, Rendong Zhang, Jundong Wu, G Chen et al.
1 citations
Frontiers in Immunology
PARP inhibition in cancer therapy
1.05
article

SLFN11 expression correlates with immune microenvironment and predicts prognosis in melanoma

Huancheng Zeng, Rendong Zhang, Jundong Wu, G Chen, Yutong Fang, Qiongzhi Jiang
article en
1 citations

Abstract

These findings provide evidence that SLFN11 is associated with immune microenvironment changes in melanoma, correlates with favorable prognosis, and may be linked to immunotherapy response, supporting its potential as a candidate biomarker and therapeutic target for further investigation.

Frontiers in ImmunologyVol. 16
Shantou University (CN), Cancer Hospital of Shantou University Medical College (CN), First Affiliated Hospital of Shantou University Medical College (CN)
Openalex Percentile: Top 18%
PARP inhibition in cancer therapy
1.05
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