Changes in T lymphocyte subsets in patients with acute neuromyelitis optica spectrum disorder
These findings underscore the pivotal role of Th1Th17 and Th17 cells in NMOSD pathogenesis. Exploring intervention strategies targeting Th17 cells or T cell activation (e.g., HLA-DR-targeted therapies) may hold clinical relevance.
Authors
- Yingzhe Shao
- Qiuxia Zhang (ORCID: https://orcid.org/0000-0001-7900-5549)
- Yang Li (ORCID: https://orcid.org/0000-0002-6925-9200)
- Linjie Zhang (ORCID: https://orcid.org/0000-0002-6100-4115)
- Ning Zhao (ORCID: https://orcid.org/0009-0009-9037-0198)
- Teng‐Yeow Tan
Institutions
- Tianjin Medical University General Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-22
- DOI
- https://doi.org/10.3389/fimmu.2025.1654533
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China