Photoinduced Reduction and Deuteration of Aryl Halides with NHC‐Boranes
Herein, an operationally simple photoinduced radical reduction of aryliodides and arylbromides using NHC‐borane as a reductant, without external radical initiator or photoredox catalyst, is reported. Mechanistic investigations indicate the key formation of an aryl radical, which undergoes facile reduction by NHC‐borane. The method demonstrates compatibility with a broad range of functional groups, providing a valuable tool for synthesis and isotopic labeling.
Authors
- Mathieu Pucheault (ORCID: https://orcid.org/0000-0002-7001-2803)
- Frédéric Robert (ORCID: https://orcid.org/0000-0003-2469-2067)
- Sandra Pinet (ORCID: https://orcid.org/0000-0001-9106-2343)
- Laurent Chabaud (ORCID: https://orcid.org/0000-0002-2590-8707)
- Gabin Lalande
Institutions
- Centre National de la Recherche Scientifique (FR)
- Université de Bordeaux (FR)
- Institut des Sciences Moléculaires (FR)
- Institut Polytechnique de Bordeaux (FR)
Publication Details
- Journal
- European Journal of Organic Chemistry
- Published
- 2025-09-21
- DOI
- https://doi.org/10.1002/ejoc.202500543
- Primary Topic
- Chemical Reactions and Isotopes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Agence Nationale de la Recherche