PREDICTION OF SEVERITY OF CORONARY ARTERY DISEASE IN PATIENTS WITH ACUTE CORONARY SYNDROME BY TRIGLYCERIDE GLUCOSE INDEX

The study was conducted to determine the prognostic ability of triglyceride glucose index for coronary heart disease in subjects with acute coronary syndrome.This retrospective observational study was done in the Cardiology Department, Punjab Institute of Cardiology/Quaid E Azam Medical College Bahawalpur from January 2024 to June 2024. Two hundred patients with acute coronary syndrome undergoing coronary angiography were analyzed.Biochemical variables were measured after 8 hours overnight fasting and TyG index was calculated. SYNTAX score was calculated by online tool through preprocedural angiograms and divided into low score and moderate-high score. Results showed that in the multivariate analysis, TyG index was independently associated for prediction of complex CAD (OR: 2.66 (95% CI: 1.86-3.70, p<0.001). According to Spearman’s correlation test revealed a weak but significantly positive relationship (r=0.019, p<0.001).Triglyceride glucose index was an independent predictor of CAD severity irrespective of diabetes status.It is concluded that TyG index and complex CAD were strongly and positively related in acute coronary syndrome patients with acute coronary syndrome.