Power and clinical utility of mesopic microperimetry analysis strategies in age‐related macular degeneration
All MMP analysis strategies outperformed VA, and MS required the least number of patients to show significant changes. This trend was consistent for both 12 and 24 months. These findings provide strong statistical arguments for the use of MMP in longitudinal within-subjects clinical trials and suggest that averaging decibels is optimal.
Authors
- Yara Lechanteur (ORCID: https://orcid.org/0000-0003-0951-4625)
- Sofie ten Brink
- Caroline C. W. Klaver (ORCID: https://orcid.org/0000-0002-2355-5258)
- Laurens Sluijterman (ORCID: https://orcid.org/0000-0001-6964-6481)
- Anita de Breuk (ORCID: https://orcid.org/0000-0001-7072-1928)
- Thomas J. Heesterbeek (ORCID: https://orcid.org/0000-0002-3232-2587)
- Francesco Cinque (ORCID: https://orcid.org/0000-0003-4354-6241)
- Jeroen Pas (ORCID: https://orcid.org/0000-0002-0302-6690)
- Mahfam Shahabi
- Carel C B Hoyng
Institutions
- Radboud University Nijmegen (NL)
- Erasmus MC (NL)
- Radboud University Medical Center (NL)
- Institute of Molecular and Clinical Ophthalmology Basel (CH)
Publication Details
- Journal
- Acta Ophthalmologica
- Published
- 2025-09-22
- DOI
- https://doi.org/10.1111/aos.70008
- Citations
- 1
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.71